Ruby on Rails is my preferred framework for the development of custom rich-internet applications.
Rails is ideal for new application development with fast, iterative development loops. Quickly integrate existing open-source projects and APIs to speed up development times.
Wordpress is an easy to use, lightweight CMS perfect for blogs and other content-heavy sites that do not require extensive customization. The extensive, existing library of plugins can keep down costs and speed development.
I'm passionate about Javascript because of the incredible development that is currently going into this language. There are exciting new server-side frameworks developing around Javascript that allow for unique types of client-side rendering.
I have headed up the design and prototyping of several web applications over the past two years. Starting with user flow, I generate mockups before beginning the design process in Fireworks. I have also built prototype pages in HTML & JS that demonstrate the full interface before passing the design off to the engineering team.